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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1979-2-26
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pubmed:abstractText |
CBA mouse-derived splenic lymphocytes treated with either beta-priopionlactone-inactivated or u.v. light-inactivated parainfluenza (sendai) virus stimulated in vitro unprimed syngeneic T-lymphocytes to differentiate into cytotoxic T-lymphocytes (CTL). The CTL generated were virus specific and H-2 restricted. For optimal CTL responses to be induced (i) a critical treatment of stimulator cells, (ii) an optimal ratio of responder to stimulator cells and (iii) an in vitro incubation period of 5 days was required. The in vitro system for the induction of primary virus-specific CTL responses may be useful to analyse the sensitization phase of H-2 restricted virus-specific CTL.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-1079922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-1082923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-16073430,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-178048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-193023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-194164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-201114,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-233918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-4151339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-4151904,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-4592605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-53265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-5544139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-60840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-60844,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-62016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/82534-63988
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0019-2805
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
763-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:82534-Animals,
pubmed-meshheading:82534-Antigens, Viral,
pubmed-meshheading:82534-Cytotoxicity, Immunologic,
pubmed-meshheading:82534-Dose-Response Relationship, Immunologic,
pubmed-meshheading:82534-Epitopes,
pubmed-meshheading:82534-H-2 Antigens,
pubmed-meshheading:82534-Kinetics,
pubmed-meshheading:82534-Macrophages,
pubmed-meshheading:82534-Mice,
pubmed-meshheading:82534-Mice, Inbred BALB C,
pubmed-meshheading:82534-Mice, Inbred CBA,
pubmed-meshheading:82534-Parainfluenza Virus 1, Human,
pubmed-meshheading:82534-T-Lymphocytes
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pubmed:year |
1978
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pubmed:articleTitle |
Primary in vitro sensitization of virus specific cytotoxic T lymphocytes.
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pubmed:publicationType |
Journal Article,
In Vitro
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