Linked Life Data

8253283

Source:http://linkedlifedata.com/resource/pubmed/id/8253283

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-1-7
pubmed:abstractText
The process of converting an egg to a multicellular organism often begins with a polarization of information within the oocyte. The cytoskeleton plays an important role in maintaining such asymmetries. Here we describe the isolation and characterization of cortices, rich in cytoskeletal elements, from the animal and vegetal poles of stage VI Xenopus oocytes. Ultrastructural and immunocytochemical analyses revealed that the 10-microns-thick isolates included a cytokeratin network, mitochondria, and other elements, found in the oocyte cortex. Furthermore, three vegetally localized mRNAs, Vg1, Xcat-2, and Xcat-3, were all found to be specifically retained within the isolated vegetal cortices, in sharp contrast to histone RNA. Our findings support the view that the vegetal cortex represents a unique cytoskeletal domain in which a rare class of maternal mRNAs becomes localized.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
160
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
554-62
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Isolated vegetal cortex from Xenopus oocytes selectively retains localized mRNAs.
pubmed:affiliation
Department of Zoology, University of Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't