Linked Life Data

8251270

Source:http://linkedlifedata.com/resource/pubmed/id/8251270

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-1-10
pubmed:abstractText
The coherent frequency (CF) of the auditory evoked response (AER) is derived using auditory clicks presented at frequencies in the range 5-47 Hz. CF and psychological performance were measured while seven subjects breathed isoflurane in doses increasing from 0% to 0.2%, 0.4% and 0.8% end-tidal concentration and then decreasing to 0%. With increasing doses of isoflurane, CF decreased and there was a decrease in within-list recognition (WLR) and category recognition (CR) scores. There was a correlation between changes in CF and WLR (P < 0.05) and between CF and category recognition (CR) (P < 0.05). A painful stimulus given in conjunction with 0.4% isoflurane caused an increase in CF, WLR and CR in some subjects. This did not reach statistical significance for the group as a whole, apart from the short word interval scores in the WLR which indicated an increase in attention (P < 0.01). Subjects did not respond with 0.8% isoflurane, either before or after painful stimulation. Reduction of end-tidal isoflurane from 0.8% to 0% caused an increase in the CF and improved performance on the psychological tests. A category generation task on recovery showed no evidence of implicit learning of words presented in conjunction with 0.8% isoflurane.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
633-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
A measure of consciousness and memory during isoflurane administration: the coherent frequency.
pubmed:affiliation
Cambridge University Department of Anaesthesia, Addenbrooke's Hospital.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't