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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-1-3
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pubmed:databankReference |
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pubmed:abstractText |
We report here the isolation and characterization of a novel human elongation factor-1 beta (EF-1 beta) gene by cDNA selection from YAC mapping on chromosome 5q12-q14. This gene is specifically transcribed in fetal brain and in skeletal muscle and is characterized by a complete sequence homology with previously described EF-1 beta cDNAs. We also assigned the loci for three other EF-1 beta isoforms, to human chromosomes 2, 15 and X. The multiple chromosomal assignments of EF-1 beta loci demonstrates the genetic heterogeneity of human EF-1 beta peptides.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
197
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
154-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8250921-Base Sequence,
pubmed-meshheading:8250921-Brain,
pubmed-meshheading:8250921-Chromosome Mapping,
pubmed-meshheading:8250921-Chromosomes, Artificial, Yeast,
pubmed-meshheading:8250921-Chromosomes, Human,
pubmed-meshheading:8250921-Chromosomes, Human, Pair 15,
pubmed-meshheading:8250921-Chromosomes, Human, Pair 2,
pubmed-meshheading:8250921-Chromosomes, Human, Pair 5,
pubmed-meshheading:8250921-DNA, Complementary,
pubmed-meshheading:8250921-Humans,
pubmed-meshheading:8250921-In Situ Hybridization,
pubmed-meshheading:8250921-Molecular Sequence Data,
pubmed-meshheading:8250921-Muscles,
pubmed-meshheading:8250921-Peptide Elongation Factor 1,
pubmed-meshheading:8250921-Peptide Elongation Factors,
pubmed-meshheading:8250921-Polymerase Chain Reaction,
pubmed-meshheading:8250921-Sequence Homology, Nucleic Acid,
pubmed-meshheading:8250921-Tissue Distribution,
pubmed-meshheading:8250921-Transcription, Genetic,
pubmed-meshheading:8250921-X Chromosome
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pubmed:year |
1993
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pubmed:articleTitle |
Human elongation factor EF-1 beta: cloning and characterization of the EF1 beta 5a gene and assignment of EF-1 beta isoforms to chromosomes 2,5,15 and X.
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pubmed:affiliation |
Institute for Molecular Genetics and Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas 77030.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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