Linked Life Data

8249873

Source:http://linkedlifedata.com/resource/pubmed/id/8249873

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-12-23
pubmed:abstractText
Oxidants in cigarette smoke accelerate metabolic turnover of ascorbic acid (AA), and thereby deplete body stores of this potent antioxidant and putative anticarcinogen in active smokers. We examined plasma AA concentrations and vitamin C intakes in nonsmokers regularly exposed to environmental tobacco smoke (ie, passive smokers; n = 44), as compared with active smokers (n = 47) and nonexposed nonsmokers (n = 50), to determine whether passive smokers also exhibit altered AA nutriture suggestive of oxidant exposure. Plasma AA concentrations in passive smokers were intermediate between those of active smokers (P = 0.0001) and nonexposed nonsmokers (P = 0.01) despite similar dietary vitamin C intakes. Hypovitaminosis C (< 23 mumol/L) was observed in 24% of active smokers and 12% of passive smokers but not in nonexposed nonsmokers. Reduced plasma AA concentrations were associated with low vitamin C intakes within smoke-exposed populations only. We conclude that chronic smoke exposure, particularly in association with low vitamin C intake, may reduce AA pools in both active and passive smokers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0002-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
886-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Reduced plasma ascorbic acid concentrations in nonsmokers regularly exposed to environmental tobacco smoke.
pubmed:affiliation
Stanford Center for Research in Disease Prevention, Stanford University Medical Center, CA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't