Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1994-1-6
pubmed:abstractText
The Asymptomatic Cardiac Ischemia Pilot (ACIP) and modified ACIP treadmill exercise protocols were developed to test patients with coronary artery disease and to linearly increase work load between stages. The physiologic changes that occurred with ACIP and modified ACIP were compared to those with the Bruce and Cornell protocols in 28 normal subjects and 16 men with coronary artery disease. The exercise protocols were randomly assigned over 2 days, and gas exchange data were obtained continuously with each test. In normal subjects, the peak heart rate, systolic blood pressure, peak oxygen consumption rate (VO2) and minute ventilation were similar for the 4 protocols tested, with exercise time shortest for the Bruce protocol in comparison with the ACIP, modified ACIP and Cornell protocols (10.2 +/- 3.1 vs 13.4 +/- 4.9, 13.9 +/- 4.5, and 15.0 +/- 4.2 minutes, respectively; p < 0.001). The difference between predicted and observed VO2 was smallest for the ACIP protocol (37.0 +/- 11.0 vs 35.8 +/- 13.5 ml/kg/min) and greatest for the Bruce protocol (41.1 +/- 11.8 vs 36.7 +/- 15.0 ml/kg/min) in normal subjects, as well as in patients with coronary artery disease (ACIP protocol 26.9 +/- 7.1 vs 22.5 +/- 6.7, and Bruce protocol 29.1 +/- 7 vs 22.6 +/- 5.7 ml/kg/min, respectively). The ratio of VO2 to work rate, expressed as a slope, was similar in normal subjects for the 4 protocols tested. However, in patients with coronary artery disease, the slope was 0.84 and 0.83 for the ACIP and modified ACIP protocols, respectively, versus 0.61 and 0.71 for the Bruce and Cornell protocols, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
715-20
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:8249851-Adult, pubmed-meshheading:8249851-Aged, pubmed-meshheading:8249851-Blood Pressure, pubmed-meshheading:8249851-Carbon Dioxide, pubmed-meshheading:8249851-Cohort Studies, pubmed-meshheading:8249851-Coronary Disease, pubmed-meshheading:8249851-Electrocardiography, pubmed-meshheading:8249851-Exercise Test, pubmed-meshheading:8249851-Exercise Tolerance, pubmed-meshheading:8249851-Female, pubmed-meshheading:8249851-Heart Rate, pubmed-meshheading:8249851-Humans, pubmed-meshheading:8249851-Male, pubmed-meshheading:8249851-Middle Aged, pubmed-meshheading:8249851-Myocardial Ischemia, pubmed-meshheading:8249851-Oxygen Consumption, pubmed-meshheading:8249851-Physical Exertion, pubmed-meshheading:8249851-Pilot Projects, pubmed-meshheading:8249851-Pulmonary Gas Exchange, pubmed-meshheading:8249851-Respiration, pubmed-meshheading:8249851-Time Factors
pubmed:year
1993
pubmed:articleTitle
Comparison of the Asymptomatic Cardiac Ischemia Pilot and modified Asymptomatic Cardiac Ischemia Pilot versus Bruce and Cornell exercise protocols.
pubmed:affiliation
Department of Internal Medicine, Saint Louis University School of Medicine, Missouri 63110-0250.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't