Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1994-1-6
|
| pubmed:abstractText |
To elucidate the reversibility of right ventricular (RV) myocardial hypertrophy in tetralogy of Fallot (TF), 30 patients underwent RV endomyocardial biopsies 1 to 25 years (mean 9.7 +/- 6.6) after corrective surgery. Myocardial cell diameter was evaluated by comparing histopathologic data with preoperative patients with TF and normal subjects. As a whole, postoperative cell diameter was smaller than that of age-matched preoperative patients with TF, and larger than that of age-matched normal subjects. In 7 patients without significant residual pulmonary stenosis whose preoperative data were also available, cell diameter significantly decreased after surgery (17.1 +/- 2.1 to 14.0 +/- 2.1 microns, p < 0.01). There was a positive correlation between postoperative cell diameter and age at study (p < 0.01). To negate the influence of age, cell diameter was expressed in terms of a percentage of age-matched normal values (percent cell diameter). There was no significant correlation between percent cell diameter and age at surgery, age at study or the follow-up periods. There were positive correlations between percent cell diameter and the following parameters: RV systolic pressure (p < 0.05), percent normal RV end-diastolic (p < 0.05) and end-systolic (p < 0.01) volumes. These results demonstrate that RV myocardial hypertrophy in TF can regress to some extent after corrective surgery if significant residual pulmonary stenosis is avoided.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0002-9149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
72
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
694-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8249847-Adolescent,
pubmed-meshheading:8249847-Adult,
pubmed-meshheading:8249847-Age Factors,
pubmed-meshheading:8249847-Biopsy,
pubmed-meshheading:8249847-Cardiac Volume,
pubmed-meshheading:8249847-Cell Size,
pubmed-meshheading:8249847-Child,
pubmed-meshheading:8249847-Child, Preschool,
pubmed-meshheading:8249847-Endocardium,
pubmed-meshheading:8249847-Follow-Up Studies,
pubmed-meshheading:8249847-Heart Septum,
pubmed-meshheading:8249847-Humans,
pubmed-meshheading:8249847-Hypertrophy, Right Ventricular,
pubmed-meshheading:8249847-Infant,
pubmed-meshheading:8249847-Myocardium,
pubmed-meshheading:8249847-Tetralogy of Fallot,
pubmed-meshheading:8249847-Ventricular Function, Right,
pubmed-meshheading:8249847-Ventricular Pressure
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Fate of right ventricular hypertrophy in tetralogy of Fallot after corrective surgery.
|
| pubmed:affiliation |
First Department of Surgery, Osaka University Medical School, Japan.
|
| pubmed:publicationType |
Journal Article
|