Linked Life Data

8249597

Source:http://linkedlifedata.com/resource/pubmed/id/8249597

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-12-28
pubmed:abstractText
The cytosolic free calcium concentration [Ca2+]i in synaptosomes was determined with the fluorescent indicator fura-2, the effects of calcium channel agonist and antagonist on intracellular Ca2+ level were studied. The cytosolic ionized calcium concentrations in resting status were between 200 nmol/L and 400 nmol/L. Cytosolic Ca2+ was elevated following increases in Ca2+ concentration in the medium, plasma membrane depolarizations induced by KCl, and the addition of glutamate and NMDA. On the other hand, the increase of cytosolic Ca2+ induced by KCl was decreased by verapamil and that induced by NMDA was decreased by MgCl2. A few critical problems in [Ca2+]i detection were also discussed.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0513-4870
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
404-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Estimation of free calcium level within synaptosomes by using fura-2 and the effect of calcium channel agonist and antagonist].
pubmed:affiliation
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't