Linked Life Data

8247327

Source:http://linkedlifedata.com/resource/pubmed/id/8247327

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-12-23
pubmed:abstractText
As the neuropeptide galanin is possibly involved in spatial learning, we investigated both the precise location and the binding features of the receptors within the rat frontal cortex using quantitative autoradiography. Galanin receptors predominated in layers I and V of medial and lateral frontal cortex with a low regional index of occupancy by endogenous galanin. These receptors might be of functional relevance since the guanylnucleotide Gpp(NH)p inhibited [125I]galanin specific binding in each labeled region in the frontal lobe. Nevertheless, the striking areal difference of expression of this effect within the medial frontal cortex suggests that [125I]galanin binding sites might be coupled to one or more types of G-proteins related to the functionally distinct cortical subareas.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
160
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[125I]galanin binding sites in the rat frontal lobe are guanine nucleotide-sensitive and display a low regional index of occupancy.
pubmed:affiliation
Laboratoire de Neurobiologie et Neuropharmacolgie du développement, CNRS URA 1121, Orsay, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't