Linked Life Data

8242572

Source:http://linkedlifedata.com/resource/pubmed/id/8242572

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11 Suppl
pubmed:dateCreated
1993-12-27
pubmed:abstractText
Colony stimulating factors (CSF) are now widely used in marrow transplantation. Randomized trials have shown that granulocyte macrophage-CSF accelerates marrow recovery after autologous marrow transplantation, resulting in fewer infections, shorter hospitalization, and lower costs. Similar results have been seen with granulocyte-CSF. Both factors also can accelerate engraftment after allogenic marrow transplantation, but there is, so far, less evidence for clinical benefit in this setting. Both granulocyte macrophage-CSF and granulocyte-CSF benefit some patients with graft failure. The recent demonstration that both granulocyte-CSF and granulocyte macrophage-CSF can mobilize large numbers of hematopoietic stem cells into peripheral blood has resulted in the widespread use of this technique as an alternative to autologous marrow transplantation. A number of colony stimulating factors, including IL-1, IL-3, and steel factor, which act on early hematopoietic progenitors, have recently been entered into clinical trials, with the hope that the progress already made with G-CSF and GM-CSF can be continued.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3387-92
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The use of colony stimulating factors in marrow transplantation.
pubmed:affiliation
Fred Hutchinson Cancer Research Center, Seattle, WA 98104-2092.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review