Linked Life Data

8241277

Source:http://linkedlifedata.com/resource/pubmed/id/8241277

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-1-4
pubmed:databankReference
pubmed:abstractText
Differential screening of a murine RNA-based lambda gt10 cDNA library with cell cycle phase-specific probes released a cDNA clone (lambda GS1) to a mRNA (1.8 kb) which is prevalent in the S phase of the cell cycle. The nucleotide sequence of the cDNA predicts a protein (RNPS1, 41 x 10(3) M(r) with two nucleic acid-binding domains separated by a proline-rich spacer. The N-terminal nucleic acid binding domain, about 80 amino acid residues in length, meets the requirements of an RNA recognition motif (RRM) including a perfect 'RNP-1 octamer'. The C-terminal nucleic acid binding domain spanning over 26 amino acid residues is prominent because it comprises three copies of the RRRS peptide. Domains of the latter type are considered to be involved in RNA and DNA-binding because comprised in many RNA and DNA-binding proteins.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
1216
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
317-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Sequence of a complete murine cDNA reflecting an S phase-prevalent transcript encoding a protein with two types of nucleic acid binding motifs.
pubmed:affiliation
German Cancer Research Center, Division of Cellular Biochemistry, Heidelberg.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't