Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-12-10
pubmed:abstractText
We previously demonstrated the presence of a long-acting antihypertensive factor (AHF) in the erythrocytes of essential hypertensive subjects (EHS). The present investigation demonstrates further that the AHF is also capable of producing a rapid and transient blood pressure lowering effect in stroke prone spontaneously hypertensive rats (from 26.8 +/- 1.7 to 20.1 +/- 1.5 kPa by 10-30 s, P < 0.001). An even more stronger antihypertensive effect could be found if the AHF prepared from normal subjects or rats was used. We also found that some hypertensive factor was present in EHS plasma, but not in normal subjects. The results of the present paper suggest that AHF deficiency and higher level of pressor substance may play an important role in the development of essential hypertension.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0371-0874
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
262-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Further studies on the depressor effect of erythrocytic antihypertensive factor].
pubmed:affiliation
Department of Physiology, Chinese Academy of Medical Sciences, Beijing.
pubmed:publicationType
Journal Article, English Abstract