Linked Life Data

8234401

Source:http://linkedlifedata.com/resource/pubmed/id/8234401

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1993-12-8
pubmed:abstractText
A method for the detection and quantitation of several undeclared drugs in herbal preparations with slimming activity is proposed. Samples containing various anorexics, hypoglycemics and antidepressants were prepared by addition of the drugs to a synthetic mixture containing the most commonly used plant powders for those preparations. Each sample was subjected to a treatment that permitted, after a simple ethanolic extraction, the identification of the drugs by TLC using three different solvent systems. A further purification of the ethanolic solution through a polyamide column allowed for quantitative analysis of the drugs by a RP-HPLC method. The analytical recovery was good (88-97%); the calibration curves were linear over a wide range of drug concentrations (30-500 micrograms/ml) (r > 0.9995); the precision was high (CV% = 0.4-2.8) as well as the accuracy (96-102%).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
678-81
pubmed:dateRevised
2007-1-29
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Herbal mixtures with claimed slimming activity: determination by TLC and HPLC of illegally added drugs.
pubmed:affiliation
Istituto di Analisi e Tecnologie Farmaceutiche ed Alimentari, Genoa University, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't