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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1993-12-20
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pubmed:abstractText |
Intravenous midazolam in doses of between 0.07 mg/kg and 0.1 mg/kg has been recommended for sedation in dentistry and some medical procedures and investigations. This study examined the variable sensitivity of patients to midazolam. One hundred and thirty-four fit but anxious patients between the ages of 16 and 63 years received midazolam intravenously for sedation for minor oral surgery. Doses required ranged from 0.04 to 0.40 mg/kg. Nineteen patients required doses less than 0.07 mg/kg; 59 patients required doses greater than 0.1 mg/kg. The mean dose per kilogram required for males was significantly less than for females. The wide variation in sensitivity to midazolam is confirmed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0030-4220
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
408-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8233417-Adolescent,
pubmed-meshheading:8233417-Adult,
pubmed-meshheading:8233417-Ambulatory Surgical Procedures,
pubmed-meshheading:8233417-Anesthesia, Dental,
pubmed-meshheading:8233417-Apicoectomy,
pubmed-meshheading:8233417-Body Weight,
pubmed-meshheading:8233417-Conscious Sedation,
pubmed-meshheading:8233417-Dental Anxiety,
pubmed-meshheading:8233417-Dose-Response Relationship, Drug,
pubmed-meshheading:8233417-Female,
pubmed-meshheading:8233417-Humans,
pubmed-meshheading:8233417-Infusions, Intravenous,
pubmed-meshheading:8233417-Male,
pubmed-meshheading:8233417-Midazolam,
pubmed-meshheading:8233417-Middle Aged,
pubmed-meshheading:8233417-Tooth Extraction
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pubmed:year |
1993
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pubmed:articleTitle |
Wide variation in patient response to midazolam sedation for outpatient oral surgery.
|
pubmed:affiliation |
Centre for the Study of Oral Disease, University of Bristol Dental School and Hospital, U.K.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|