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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1993-11-29
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pubmed:abstractText |
Seventeen of 19 patients (67 +/- 8 yr, 17 males and 2 females) had more than 75% unilateral stenosis or occlusion of the internal carotid or middle cerebral artery and two patients had carotid endarterectomy that previously had 90% stenosis of the internal carotid artery. They were studied during upright 99mTc-HMPAO brain SPECT. HMPA was injected immediately after arising from a supine position. Patients were classified into Group A (n = 10) with occlusion of the internal carotid or the middle cerebral artery or Group B (n = 9) with more than 75% unilateral stenosis of the internal carotid or the middle cerebral artery and with carotid endarterectomy. Additional cerebral blood flow perfusion abnormalities between upright and supine 99mTc-HMPAO brain SPECT were detected in seven patients in Group A and in only one patient in Group B. Semiquantitative analysis showed that the asymmetric ratios between upright and supine positions changed significantly in Group A from 0.82 +/- 0.15 to 0.89 +/- 0.10 (p < 0.01), but not in Group B, from 0.89 +/- 0.11 to 0.92 +/- 0.12 (ns). Additional perfusion abnormalities were relevant to occlusion of the internal carotid or middle cerebral artery indicated postural cerebral hypoperfusion. We conclude that upright 99mTc-HMPAO brain SPECT visualizes postural cerebral hypoperfusion possibly related to silent cerebral ischemia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0161-5505
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1931-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8229237-Aged,
pubmed-meshheading:8229237-Brain,
pubmed-meshheading:8229237-Carotid Artery, Internal,
pubmed-meshheading:8229237-Carotid Artery Diseases,
pubmed-meshheading:8229237-Cerebrovascular Circulation,
pubmed-meshheading:8229237-Cerebrovascular Disorders,
pubmed-meshheading:8229237-Constriction, Pathologic,
pubmed-meshheading:8229237-Female,
pubmed-meshheading:8229237-Humans,
pubmed-meshheading:8229237-Male,
pubmed-meshheading:8229237-Middle Aged,
pubmed-meshheading:8229237-Organotechnetium Compounds,
pubmed-meshheading:8229237-Oximes,
pubmed-meshheading:8229237-Posture,
pubmed-meshheading:8229237-Technetium Tc 99m Exametazime,
pubmed-meshheading:8229237-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
1993
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pubmed:articleTitle |
Detection of postural cerebral hypoperfusion with technetium-99m-HMPAO brain SPECT in patients with cerebrovascular disease.
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pubmed:affiliation |
Department of Radiology, Medical School, Osaka University, Japan.
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pubmed:publicationType |
Journal Article
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