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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-11-29
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pubmed:abstractText |
The role of ciprofloxacin and trimethoprim-sulfamethoxazole (TMP-SMZ) was evaluated in empiric treatment of uncomplicated Salmonella enteritis in a comparative, double-blind trial. Patients were randomized to receive ciprofloxacin (500 mg), TMP-SMZ (160/800 mg), or placebo orally twice daily for 5 days. There were 65 evaluatable patients with acute, uncomplicated, culture-confirmed Salmonella enteritis. Duration of diarrhea, abdominal pain, or vomiting and time to defervescence were not significantly different for patients treated with ciprofloxacin, TMP-SMZ, or placebo; there also were no significant differences with respect to full resolution of symptoms for ciprofloxacin versus placebo (point estimate, 0.2 days; 95% confidence interval [CI], -0.5 to 0.9 days) or for TMP-SMZ versus placebo (point estimate, 0.2 days; 95% CI, -1.0 to 0.6 days). The rate of clearance of salmonellae from stools was not significantly different among the groups.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
168
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1304-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8228368-Acute Disease,
pubmed-meshheading:8228368-Adult,
pubmed-meshheading:8228368-Ciprofloxacin,
pubmed-meshheading:8228368-Double-Blind Method,
pubmed-meshheading:8228368-Drug Combinations,
pubmed-meshheading:8228368-Enteritis,
pubmed-meshheading:8228368-Feces,
pubmed-meshheading:8228368-Female,
pubmed-meshheading:8228368-Humans,
pubmed-meshheading:8228368-Male,
pubmed-meshheading:8228368-Middle Aged,
pubmed-meshheading:8228368-Salmonella Infections,
pubmed-meshheading:8228368-Trimethoprim-Sulfamethoxazole Combination
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pubmed:year |
1993
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pubmed:articleTitle |
Ciprofloxacin and trimethoprim-sulfamethoxazole versus placebo in acute uncomplicated Salmonella enteritis: a double-blind trial.
|
pubmed:affiliation |
Dept. of Medicine, Hospital de Mútua de Terrassa, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|