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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1993-12-16
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pubmed:abstractText |
In a prospective randomized trial involving 63 patients with bleeding peptic ulcer, we assessed whether the addition of 1% polidocanol improved the results achieved by 1/10(4) adrenaline alone for injection therapy. The inclusion criterion was the presence of active arterial bleeding or a nonbleeding visible vessel at emergency endoscopy. Thirty patients were treated with 1/10(4) adrenaline (group A) and 33 with adrenaline plus 1% polidocanol (group B). Initial hemostasis was achieved in 97% of cases in both groups and permanent hemostasis in 87% patients in group A and in 76% in group B (p = NS). Mortality was 6% in group A and 3% in group B. There were no differences between the two groups regarding requirements for emergency surgery, the number of transfusions, or the length of hospital stay. One patient in group B had a perforation. No other relevant complications were noted. In conclusion, combined therapy does not improve the results achieved with adrenaline alone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0192-0790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-200
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8228078-Epinephrine,
pubmed-meshheading:8228078-Female,
pubmed-meshheading:8228078-Hemostasis, Endoscopic,
pubmed-meshheading:8228078-Humans,
pubmed-meshheading:8228078-Male,
pubmed-meshheading:8228078-Middle Aged,
pubmed-meshheading:8228078-Peptic Ulcer Hemorrhage,
pubmed-meshheading:8228078-Polyethylene Glycols,
pubmed-meshheading:8228078-Prospective Studies,
pubmed-meshheading:8228078-Sclerosing Solutions,
pubmed-meshheading:8228078-Treatment Outcome
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pubmed:year |
1993
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pubmed:articleTitle |
Endoscopic injection therapy of bleeding ulcer: a prospective and randomized comparison of adrenaline alone or with polidocanol.
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pubmed:affiliation |
Department of Gastroenterology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|