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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1993-12-6
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pubmed:abstractText |
The regulation of the trabecular meshwork's extracellular matrix is poorly understood and may involve a family of secreted proteinases, the matrix metalloproteinases. Because the trabecular extracellular matrix has been hypothesized to affect intraocular pressure, an evaluation was made of the ability of two cellular modulators to change the levels of matrix metalloproteinases in the medium of human trabecular meshwork organ explant cultures.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3386-95
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8225873-Aged,
pubmed-meshheading:8225873-Collagenases,
pubmed-meshheading:8225873-Culture Media,
pubmed-meshheading:8225873-Dexamethasone,
pubmed-meshheading:8225873-Extracellular Matrix,
pubmed-meshheading:8225873-Gelatinases,
pubmed-meshheading:8225873-Glycoproteins,
pubmed-meshheading:8225873-Humans,
pubmed-meshheading:8225873-Interleukin-1,
pubmed-meshheading:8225873-Matrix Metalloproteinase 3,
pubmed-meshheading:8225873-Metalloendopeptidases,
pubmed-meshheading:8225873-Organ Culture Techniques,
pubmed-meshheading:8225873-Recombinant Proteins,
pubmed-meshheading:8225873-Tissue Inhibitor of Metalloproteinases,
pubmed-meshheading:8225873-Trabecular Meshwork
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pubmed:year |
1993
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pubmed:articleTitle |
Regulation of the levels of human trabecular matrix metalloproteinases and inhibitor by interleukin-1 and dexamethasone.
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pubmed:affiliation |
Casey Eye Institute, Oregon Health Sciences University, Portland 97201.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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