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| pubmed-article:8224542 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8224542 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:8224542 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
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| pubmed-article:8224542 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8224542 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8224542 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8224542 | pubmed:dateCreated | 1993-12-16 | lld:pubmed |
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| pubmed-article:8224542 | pubmed:abstractText | The gene con-6 of Neurospora crassa is expressed during the formation of asexual spores (conidia), but it is not expressed in mycelium. con-6 mRNA appears upon induction of conidiation and reaches high levels at the late stages of conidiation, and in mature conidia. The CON6 polypeptide and a CON6-beta-Gal fusion protein were present at high levels only in free conidia. Shortly after spore germination con-6 mRNA disappears and the CON6 polypeptide is degraded. CON6 is a small, hydrophilic polypeptide containing a repeat sequence; it not homologous to any known protein but has features resembling the late embryogenesis abundant proteins of maize. Inactivation of con-6 by the repeat-induced point mutation process had no demonstrable effect on formation or germination of conidia. Upstream sequence comparisons for con-6 and other con genes identified a common potential regulatory sequence, designated CRS-B. DNA mobility shift analyses with cell extracts identified a factor that bound to synthetic DNA fragments containing this sequence. This binding factor was present in mycelium but not in conidiating cultures. Experiments with independent integrated con-6'-'lacZ translational fusions revealed substantial variability of expression among transformants carrying identical fusion constructs: This variability may be due to the differential methylation of transformant DNA noted by others. | lld:pubmed |
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| pubmed-article:8224542 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8224542 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8224542 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8224542 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8224542 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:8224542 | pubmed:issn | 0012-1606 | lld:pubmed |
| pubmed-article:8224542 | pubmed:author | pubmed-author:YanofskyCC | lld:pubmed |
| pubmed-article:8224542 | pubmed:author | pubmed-author:WhiteB TBT | lld:pubmed |
| pubmed-article:8224542 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8224542 | pubmed:volume | 160 | lld:pubmed |
| pubmed-article:8224542 | pubmed:geneSymbol | con-6 | lld:pubmed |
| pubmed-article:8224542 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8224542 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8224542 | pubmed:pagination | 254-64 | lld:pubmed |
| pubmed-article:8224542 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:8224542 | pubmed:meshHeading | pubmed-meshheading:8224542-... | lld:pubmed |
| pubmed-article:8224542 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8224542 | pubmed:articleTitle | Structural characterization and expression analysis of the Neurospora conidiation gene con-6. | lld:pubmed |
| pubmed-article:8224542 | pubmed:affiliation | Department of Biological Sciences, Stanford University, California 94305. | lld:pubmed |
| pubmed-article:8224542 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8224542 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8224542 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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