rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
1993-12-7
|
pubmed:abstractText |
Nitric oxide released by a calcium dependent constitutive NO synthase in endocardial endothelial cells exerts characteristic effects on myocardial contraction. Interleukin 1 beta (IL-1) induces the expression of a different calcium independent NO synthase in several tissues. Activity of the latter enzyme has recently been identified in cardiac myocytes but its functional effects are unknown. The aim of this study was to investigate the effects of IL-1 on contraction of isolated ferret papillary muscle preparations.
|
pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0008-6363
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1486-90
|
pubmed:dateRevised |
2009-9-29
|
pubmed:meshHeading |
pubmed-meshheading:8221802-Acebutolol,
pubmed-meshheading:8221802-Animals,
pubmed-meshheading:8221802-Culture Techniques,
pubmed-meshheading:8221802-Cyclic GMP,
pubmed-meshheading:8221802-Dexamethasone,
pubmed-meshheading:8221802-Electric Stimulation,
pubmed-meshheading:8221802-Ferrets,
pubmed-meshheading:8221802-Indomethacin,
pubmed-meshheading:8221802-Interleukin-1,
pubmed-meshheading:8221802-Myocardial Contraction,
pubmed-meshheading:8221802-Nitric Oxide,
pubmed-meshheading:8221802-Papillary Muscles
|
pubmed:year |
1993
|
pubmed:articleTitle |
Interleukin-1 beta modulates myocardial contraction via dexamethasone sensitive production of nitric oxide.
|
pubmed:affiliation |
Cardiovascular Sciences Research Group, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|