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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1993-12-17
|
| pubmed:abstractText |
In this study, 168 patients who underwent curative resection for gastric cancer with prognostic serosal invasion [ps(+)] and 150 without prognostic serosal invasion [ps(-)] were analyzed separately to determine the prognostic importance of clinicopathological factors, and identify which patients were at high risk of recurrence. A multivariate analysis of survival time using Cox's proportional hazard model revealed the important prognostic factors to be: Lymph node involvement, the classification of gross appearance, macroscopic serosal invasion, and interstitial connective tissue in the ps(+) group; and lymph node involvement, macroscopic serosal invasion, and venous invasion in the ps(-) group. We proposed a risk score of recurrence based on the results of a further multivariate analysis called Hayashi's Quantification Analysis II, in which recurrence was chosen as an objective variable and the above prognostic factors were chosen as explanatory variables. Eighty-four percent of the patients with a score of 0 or higher in the ps(+) group and 83% of those with a score of +6 or higher in the ps(-) group showed recurrence. Thus, we believe that this score is useful for identifying those patients at high risk of recurrence, who should receive intensive chemotherapy even after curative resection.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0941-1291
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
759-64
|
| pubmed:dateRevised |
2006-8-3
|
| pubmed:meshHeading |
pubmed-meshheading:8219607-Female,
pubmed-meshheading:8219607-Follow-Up Studies,
pubmed-meshheading:8219607-Gastrectomy,
pubmed-meshheading:8219607-Gastric Mucosa,
pubmed-meshheading:8219607-Humans,
pubmed-meshheading:8219607-Liver Neoplasms,
pubmed-meshheading:8219607-Lymphatic Metastasis,
pubmed-meshheading:8219607-Male,
pubmed-meshheading:8219607-Multivariate Analysis,
pubmed-meshheading:8219607-Neoplasm Invasiveness,
pubmed-meshheading:8219607-Neoplasm Recurrence, Local,
pubmed-meshheading:8219607-Neoplasm Staging,
pubmed-meshheading:8219607-Peritoneal Neoplasms,
pubmed-meshheading:8219607-Proportional Hazards Models,
pubmed-meshheading:8219607-Risk Factors,
pubmed-meshheading:8219607-Stomach Neoplasms,
pubmed-meshheading:8219607-Survival Analysis,
pubmed-meshheading:8219607-Survival Rate
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Proposal of a risk score for recurrence in patients with curatively resected gastric cancer.
|
| pubmed:affiliation |
First Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
|
| pubmed:publicationType |
Journal Article
|