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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1993-12-22
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pubmed:abstractText |
Of 131 patients with non-segmental vitiligo studied, 29 (22%) had a family history of this disorder. The clinical features and HLA antigens were assessed, and a comparison made between patients with familial and those with non-familial, non-segmental vitiligo. Familial patients developed skin lesions significantly earlier than non-familial patients. There was a significant association between HLA-B46 and familial non-segmental vitiligo, whereas HLA-A31 and CW4 were found in non-familial patients. The differences in clinical features and HLA phenotypes suggest heterogeneity in the pathogenic process between familial and non-familial vitiligo patients.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0007-0963
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
129
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
408-10
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8217754-Adolescent,
pubmed-meshheading:8217754-Adult,
pubmed-meshheading:8217754-Antibodies, Antinuclear,
pubmed-meshheading:8217754-Autoantibodies,
pubmed-meshheading:8217754-Child,
pubmed-meshheading:8217754-Child, Preschool,
pubmed-meshheading:8217754-Genetic Diseases, Inborn,
pubmed-meshheading:8217754-HLA Antigens,
pubmed-meshheading:8217754-Humans,
pubmed-meshheading:8217754-Infant,
pubmed-meshheading:8217754-Microsomes,
pubmed-meshheading:8217754-Middle Aged,
pubmed-meshheading:8217754-Phenotype,
pubmed-meshheading:8217754-Thyroglobulin,
pubmed-meshheading:8217754-Vitiligo
|
pubmed:year |
1993
|
pubmed:articleTitle |
Difference in clinical features and HLA antigens between familial and non-familial vitiligo of non-segmental type.
|
pubmed:affiliation |
Department of Dermatology, Tokyo University Branch Hospital, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|