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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1993-11-10
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pubmed:abstractText |
We describe a systemic lupus erythematosus (SLE) patient who for several years had typical SLE features and positive antinuclear antibodies (ANA), including anti-native DNA. Over the course of a year, 4 years after the SLE was diagnosed, the ANA disappeared and antibodies to cytoplasmic component ribosomal P protein (anti-P) appeared. Associated with the appearance of anti-P antibodies was the development of biochemical evidence of liver disease, later shown histologically to be chronic active hepatitis. The temporal relationship between the occurrence of anti-P antibodies and the development of liver disease raises the possibility of a role for anti-P antibodies in liver disease.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1325-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8216426-Adult,
pubmed-meshheading:8216426-Autoantibodies,
pubmed-meshheading:8216426-Blotting, Western,
pubmed-meshheading:8216426-Chronic Disease,
pubmed-meshheading:8216426-Female,
pubmed-meshheading:8216426-Hepatitis,
pubmed-meshheading:8216426-Humans,
pubmed-meshheading:8216426-Lupus Erythematosus, Systemic,
pubmed-meshheading:8216426-Protozoan Proteins,
pubmed-meshheading:8216426-Ribosomal Proteins
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pubmed:year |
1993
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pubmed:articleTitle |
Concomitant development of chronic active hepatitis and antibodies to ribosomal P proteins in a patient with systemic lupus erythematosus.
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pubmed:affiliation |
Arthritis/Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City 73140.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
|