Linked Life Data

8212998

Source:http://linkedlifedata.com/resource/pubmed/id/8212998

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-10-28
pubmed:abstractText
Although there are many reports providing evidence for platelet hyperactivity during acute infarctive crisis in sickle cell disease, little attention has been paid to the study of platelet release reaction in steady state. Plasma levels of the alpha-granule constituents beta-thromboglobulin and platelet factor 4 were measured in patients with sickle cell anemia during steady state and vaso-occlusive crisis in order to determine in vivo platelet activity. Significantly higher plasma levels of both proteins were found in steady state and in crisis when compared with those of normal controls. Platelet hyperactivity was also found to be more vigorous in painful crisis, suggesting a possible therapeutic role for drugs that inhibit platelet function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5792
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
180-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Study of platelet function in patients with sickle cell anemia during steady state and vaso-occlusive crisis.
pubmed:affiliation
Department of Pathologic Physiology, Athens University School of Medicine, Greece.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't