Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1993-10-29
|
pubmed:abstractText |
Of 79 children born to asymptomatic HBsAg chronic carrier mothers and vaccinated at birth against hepatitis B, a total of 71, 66 and 56 could be serologically assessed after 1, 5 and 7 years, respectively. Anti-HBs titres (geometric means) of responders decreased from 2475 to 143 IU l-1 between 1 and 5 years of age and dropped to 82 IU l-1 by 7 years. At this time, a booster dose given to 34 children who showed anti-HBs titres lower or slightly higher than 100 IU l-1 significantly increased titres from 34 to 2985 IU l-1 (p < 0.001). Children whose titres following perinatal vaccination reached 100 to 1000 IU l-1 or above 1000 IU l-1 maintained protective levels (> 10 IU l-1) for 3 and 5 years, respectively. As in adults, anti-HBs titres recorded after the initial vaccination indicate the time at which infants should receive booster vaccination.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0264-410X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1033-6
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8212823-Child,
pubmed-meshheading:8212823-Child, Preschool,
pubmed-meshheading:8212823-Follow-Up Studies,
pubmed-meshheading:8212823-Hepatitis B,
pubmed-meshheading:8212823-Hepatitis B Antibodies,
pubmed-meshheading:8212823-Hepatitis B Vaccines,
pubmed-meshheading:8212823-Humans,
pubmed-meshheading:8212823-Immunization, Secondary,
pubmed-meshheading:8212823-Immunization Schedule,
pubmed-meshheading:8212823-Infant,
pubmed-meshheading:8212823-Infant, Newborn,
pubmed-meshheading:8212823-Time Factors,
pubmed-meshheading:8212823-Vaccination
|
pubmed:year |
1993
|
pubmed:articleTitle |
A 7-year follow-up of newborns vaccinated against hepatitis B.
|
pubmed:affiliation |
Department of Gynecology and Obstetrics, Hospital Son Dureta, Palma de Mallorca, Spain.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|