Linked Life Data

8207971

Source:http://linkedlifedata.com/resource/pubmed/id/8207971

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-7-12
pubmed:abstractText
The interaction of blood-borne lymphocytes with blood vascular endothelial cells is a fundamental component of lymphocyte circulation. The role of lymphatic endothelial cells is less certain. These studies describe the isolation, characterization and lymphocyte binding capacity of efferent lymphatic endothelial cells from ovine mesenteric lymphatic vessels. Lymphatic endothelial cells had anti-thrombin 3, von Willebrand Factor and MHC I on their surface. The cells also actively metabolized acetylated low density lipoprotein. The morphological appearance was indistinguishable from blood vascular endothelium but quite different from cultured smooth muscle cells. Lymphocyte binding to lymphatic endothelial cells was not significantly different from binding to carotid artery or jugular vein endothelial cells. The degree of binding in all cases could be enhanced by incubating endothelial cells in medium containing rh TNF-alpha (recombinant human tumor necrosis factor alpha).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0024-7766
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Characterization of ovine lymphatic endothelial cells and their interactions with lymphocytes.
pubmed:affiliation
Department of Immunology, University of Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article, Comparative Study