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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1994-7-7
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pubmed:abstractText |
Our purpose was to examine the effects of RU 486 and leuprolide acetate on uterine artery blood flow and uterine volume.
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Americas,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/California,
http://linkedlifedata.com/resource/pubmed/keyword/Developed Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Endocrine System,
http://linkedlifedata.com/resource/pubmed/keyword/Examinations And Diagnoses,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia, Female,
http://linkedlifedata.com/resource/pubmed/keyword/Hormone Antagonists,
http://linkedlifedata.com/resource/pubmed/keyword/Hormones,
http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Examinations And Diagnoses,
http://linkedlifedata.com/resource/pubmed/keyword/North America,
http://linkedlifedata.com/resource/pubmed/keyword/Northern America,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Prospective Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Research Report,
http://linkedlifedata.com/resource/pubmed/keyword/Ru-486,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Treatment,
http://linkedlifedata.com/resource/pubmed/keyword/United States,
http://linkedlifedata.com/resource/pubmed/keyword/Urogenital System,
http://linkedlifedata.com/resource/pubmed/keyword/Uterine Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Uterus
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0002-9378
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
170
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1623-7; discussion 1627-8
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pubmed:dateRevised |
2004-11-17
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pubmed:otherAbstract |
PIP: Fourteen women with uterine fibroids and scheduled to undergo either myomectomy or hysterectomy were randomly assigned to take RU-486 and leuprolide acetate over a period of three months to determine their effects upon uterine artery blood flow and uterine volume. Eight patients received 25 mg of RU-486 per day and six patients received 3.75 mg/month of leuprolide acetate over the same period. Uterine artery blood flow change was determined by resistive index by means of vaginal color Doppler ultrasonography, while uterine volume was measured before and during the study with abdominal ultrasonography. Blood flow decreased 40% among those taking RU-486 compared to 21% among those administered leuprolide acetate. Uterine volume decreased significantly for both groups without significant difference in the extent of decrease between groups. Study findings would support the hypothesis that a significant decrease in uterine artery blood flow may provide a mechanism for the decrease in uterine size and the decrease in uterine blood loss at the time of surgery.
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pubmed:meshHeading |
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pubmed:year |
1994
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pubmed:articleTitle |
The effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Kaiser Permanente, University of California, San Diego 92103.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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