Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0007452,
umls-concept:C0024264,
umls-concept:C0025260,
umls-concept:C0026131,
umls-concept:C0031437,
umls-concept:C0039194,
umls-concept:C0085358,
umls-concept:C0870432,
umls-concept:C1332717,
umls-concept:C1413244,
umls-concept:C1555465,
umls-concept:C1705417,
umls-concept:C1706438,
umls-concept:C2698600
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pubmed:issue |
1
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pubmed:dateCreated |
1994-7-1
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pubmed:abstractText |
The phenotype of bovine milk lymphocytes was investigated and compared to peripheral blood lymphocytes using monoclonal antibodies specific for bovine leukocyte differentiation antigens and flow cytometry. T lymphocytes traffic selectively into bovine milk while B lymphocytes represent a minor population in milk by comparison to peripheral blood. The vast majority of T cells in milk express alpha beta T cell receptors and are predominantly CD8+. T cells in milk express twofold higher levels of CD2 and fivefold lower levels of CD45R, characteristics associated with memory T cells. Grouping of cows by lactational stage and analysis of lymphocyte subpopulation percentages indicated that CD4+ T cells are present in relatively low numbers in milk of cows in the first 50 days of lactation and have a significant tendency to increase in number as lactation progresses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0008-8749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
156
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
245-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8200039-Animals,
pubmed-meshheading:8200039-Antigens, CD,
pubmed-meshheading:8200039-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:8200039-Cattle,
pubmed-meshheading:8200039-Female,
pubmed-meshheading:8200039-Immunologic Memory,
pubmed-meshheading:8200039-Lactation,
pubmed-meshheading:8200039-Milk,
pubmed-meshheading:8200039-T-Lymphocyte Subsets
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pubmed:year |
1994
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pubmed:articleTitle |
Bovine milk lymphocytes display the phenotype of memory T cells and are predominantly CD8+.
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pubmed:affiliation |
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California at Davis 95616-8739.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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