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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1994-7-7
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pubmed:abstractText |
Nm23 is a gene associated with low tumor metastatic potential and has been proposed to be a metastasis suppressor gene. Nm23 is localized on chromosome 17q21.3-22, whereas the p53 suppressor gene is on 17p13. Allelic deletions of chromosome 17 have been related to the progression of colorectal carcinomas. The purpose of this study was to analyze the allelic deletions of Nm23 and p53 in colorectal carcinomas and to assess their prognostic significance in the evolution of the patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2913-21
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8199988-Adenocarcinoma,
pubmed-meshheading:8199988-Aged,
pubmed-meshheading:8199988-Alleles,
pubmed-meshheading:8199988-Aneuploidy,
pubmed-meshheading:8199988-Base Sequence,
pubmed-meshheading:8199988-Blotting, Southern,
pubmed-meshheading:8199988-Chromosome Deletion,
pubmed-meshheading:8199988-Chromosome Mapping,
pubmed-meshheading:8199988-Chromosomes, Human, Pair 17,
pubmed-meshheading:8199988-Colorectal Neoplasms,
pubmed-meshheading:8199988-Female,
pubmed-meshheading:8199988-Gene Deletion,
pubmed-meshheading:8199988-Genes, p53,
pubmed-meshheading:8199988-Heterozygote,
pubmed-meshheading:8199988-Humans,
pubmed-meshheading:8199988-Male,
pubmed-meshheading:8199988-Molecular Sequence Data,
pubmed-meshheading:8199988-Monomeric GTP-Binding Proteins,
pubmed-meshheading:8199988-NM23 Nucleoside Diphosphate Kinases,
pubmed-meshheading:8199988-Nucleoside-Diphosphate Kinase,
pubmed-meshheading:8199988-Polymerase Chain Reaction,
pubmed-meshheading:8199988-Prognosis,
pubmed-meshheading:8199988-Transcription Factors
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pubmed:year |
1994
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pubmed:articleTitle |
Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.
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pubmed:affiliation |
Department of Anatomic Pathology, Hospital Clinico y Provincial, School of Medicine, University of Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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