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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8097
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pubmed:dateCreated |
1979-1-24
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pubmed:abstractText |
In normotensive subjects an inverse correlation was observed between an index of sympathetic nervous activity (the plasma-noradrenaline concentration during physical exercise) and reactivity to exogenous noradrenaline. This relationship was invariably disturbed in age-matched patients with essential hypertension. Multiple-regression analysis revealed a highly significant correlation between the combination of both factors and the height of mean arterial blood-pressure (r=0.91). The findings suggest that sympathetic nervous activity and pressor response to noradrenaline together form an important determinant of the arterial blood-pressure level. An inverse relationship could be demonstrated between plasma-renin concentration and pressor response to angiotensin II in normotensives, and this relationship was unchanged in hypertensive patients. Therefore angiotensin II does not appear to contribute directly to high blood-pressure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
959-63
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:81987-Adult,
pubmed-meshheading:81987-Angiotensin II,
pubmed-meshheading:81987-Blood Pressure,
pubmed-meshheading:81987-Female,
pubmed-meshheading:81987-Hormones,
pubmed-meshheading:81987-Humans,
pubmed-meshheading:81987-Hypertension,
pubmed-meshheading:81987-Male,
pubmed-meshheading:81987-Middle Aged,
pubmed-meshheading:81987-Norepinephrine,
pubmed-meshheading:81987-Physical Exertion,
pubmed-meshheading:81987-Regression Analysis,
pubmed-meshheading:81987-Renin,
pubmed-meshheading:81987-Rest,
pubmed-meshheading:81987-Sympathetic Nervous System
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pubmed:year |
1978
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pubmed:articleTitle |
Sympathetic nervous system and blood-pressure control in essential hypertension.
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pubmed:publicationType |
Journal Article,
Comparative Study
|