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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1994-7-6
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pubmed:abstractText |
Immune surveillance poses the existence of a recirculating pool of lymphocytes that migrate randomly through somatic tissues. Upon recognition of neoantigens on malignantly transformed cells, lymphocytes proceed to attack and destroy degenerate cells before a tumor emerges. Here, J. Wayne Streilein and colleagues review the effects of ultraviolet B irradiation on the induction of cutaneous immunity in the skin of mice and humans. Furthermore, they discuss the possibility of a genetic predisposition to skin cancer, mediated by a defect in the normal process by which contact hypersensitivity, and therefore immunogenicity, is elicited.
|
pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0167-5699
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
174-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8198709-Animals,
pubmed-meshheading:8198709-Humans,
pubmed-meshheading:8198709-Immunologic Surveillance,
pubmed-meshheading:8198709-Mice,
pubmed-meshheading:8198709-Neoplasms, Radiation-Induced,
pubmed-meshheading:8198709-Skin,
pubmed-meshheading:8198709-Skin Neoplasms,
pubmed-meshheading:8198709-Sunlight,
pubmed-meshheading:8198709-Ultraviolet Rays
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pubmed:year |
1994
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pubmed:articleTitle |
Immune surveillance and sunlight-induced skin cancer.
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pubmed:affiliation |
Schepens Eye Research Institute, Boston, MA 02114.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|