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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-6-27
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pubmed:abstractText |
The incidence of Hirschsprung's disease was studied in approximately 1.5 million consecutive live births in Denmark by hospital records. A diagnosis of Hirschsprung's disease required a histologic verified absence of ganglion cells in either biopsy or surgical colonic specimens. The incidence of Hirschsprung's disease was found to be 0.140 per 1000 live births (1:7,165) with a male: female ratio of 4.1:1 in short segment, and 2.4:1 in long segment Hirschsprung's disease (p = 0.36). Maternal age and birth order were unimportant factors. The association of Hirschsprung's disease and Down's syndrome was seen in 9 of the 207 patients and may represent a real association, whereas the association with congenital heart defects seen in 2% (not including patients with Down's syndrome) is more doubtful. A mortality of 16% among the patients with Hirschsprung's disease emphasizes the extreme importance of early diagnosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
68-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8193476-Abnormalities, Multiple,
pubmed-meshheading:8193476-Adolescent,
pubmed-meshheading:8193476-Child,
pubmed-meshheading:8193476-Denmark,
pubmed-meshheading:8193476-Female,
pubmed-meshheading:8193476-Hirschsprung Disease,
pubmed-meshheading:8193476-Humans,
pubmed-meshheading:8193476-Incidence,
pubmed-meshheading:8193476-Infant,
pubmed-meshheading:8193476-Male
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pubmed:year |
1994
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pubmed:articleTitle |
An epidemiological study of Hirschsprung's disease and additional anomalies.
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pubmed:affiliation |
Department of Neurology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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