Linked Life Data

8191521

Source:http://linkedlifedata.com/resource/pubmed/id/8191521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-6-17
pubmed:abstractText
Thymalin, a polypeptide drug obtained by extraction from cattle thymus, was used in therapy of 44 children with acute and relapsing herpetic stomatitis. Laboratory studies included direct analysis of fluorescent antibodies in buccal mucosa epithelium to verify the clinical diagnosis and enzyme immunoassay of specific antigen in salivary samples before and after therapy. Enzyme immunoassay was also used to assay antibodies to herpes simplex virus in the blood serum over the course of treatment. Immunity status over the course of treatment was assessed by indirect immunofluorescence with monoclonal antibodies used to study lymphocyte subpopulations CD4+ inductor-helpers, CD8+ natural killers, and CD4+/CD8+ ratio. Thumalin therapy was not conducive to a rapid abatement of acute symptoms in stomatitis; but such therapy is justified, for in helps attain a stable antirelapse effect in children at a high risk of developing stomatitis recurrences.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0039-1735
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Thymalin in the treatment of herpetic stomatitis in children].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract