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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1994-6-20
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pubmed:abstractText |
The role of the influenza A virus panhandle structure formed from the 3'- and 5'-terminal nucleotides of virion RNA segments was studied in both an RNA polymerase binding assay and an in vitro transcription assay. Despite recent indications that promoter activity is simply a function of the 3'-terminal sequence of virion RNA, our results show that both 3'- and 5'-terminal sequences are involved in the initiation of transcription. We propose a new model for the initiation of transcription which has implications for the mechanisms by which influenza virus transcription, replication, and polyadenylation may be regulated in the infected cell.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-1469351,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-1469370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-1618740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-1626419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-1727600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-2033659,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-2052614,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-2585601,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-3436966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-3462695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-4519026,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-493121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-498272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-6191756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-6253885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-6261960,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-6351727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-6823015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-6950380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-7010182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-7064346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-7278968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-7358274,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-7407922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-8107213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-8317146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-8336121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8189550-929980
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4092-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8189550-Animals,
pubmed-meshheading:8189550-Base Sequence,
pubmed-meshheading:8189550-DNA-Directed RNA Polymerases,
pubmed-meshheading:8189550-Humans,
pubmed-meshheading:8189550-Influenza A virus,
pubmed-meshheading:8189550-Models, Genetic,
pubmed-meshheading:8189550-Molecular Sequence Data,
pubmed-meshheading:8189550-Mutagenesis, Site-Directed,
pubmed-meshheading:8189550-Nucleic Acid Conformation,
pubmed-meshheading:8189550-Promoter Regions, Genetic,
pubmed-meshheading:8189550-RNA, Messenger,
pubmed-meshheading:8189550-RNA, Viral,
pubmed-meshheading:8189550-Transcription, Genetic
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pubmed:year |
1994
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pubmed:articleTitle |
The influenza virus panhandle is involved in the initiation of transcription.
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pubmed:affiliation |
Chemical Pathology Unit, Sir William Dunn School of Pathology, University of Oxford, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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