Linked Life Data

818801

Source:http://linkedlifedata.com/resource/pubmed/id/818801

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-8-2
pubmed:abstractText
Lymphoreticular cell (LRC) infiltration into tumour masses at different stages of growth after transplantation was studied in canine transmissible venereal sarcoma (CTVS). The percent viable LRC of total viable cells in tumour suspensions shows an inverse correlation with the logs of tumour mass of adult dogs (R = -0.475, phi = 28, P less than 0.01), which suggests that the degree of LRC infiltration is a measure of the host immune response. However, an estimate of the surface area (S.A.) of the tumour rather well perfused with blood elements based on the formula S.A. = 5.43 (tumour mass in g)2/3 showed that the LRC mass present in a tumour was a function of its surface area. Thus, the inverse correlation of the percent viable LRC's in a viable tumour cell suspension to the log of the CTVS mass might not necessarily indicate that the infiltrated LRC's were active as immune effector cells. The correlation does show that, as the CTVS size increases, the volume of the necrotic center increases more rapidly than the volume perfused with blood and, therefore, the percent viable LRC's in CTVS decreases with CTVS size increase.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0340-6075
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-204
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Quantitative study of lymphoreticular infiltration into canine transmissible venereal sarcoma.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.