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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-6-23
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pubmed:abstractText |
We have compared the antigen-presenting capacity of macrophages from congenic BALB/c.Bcgr and BALB/c.Bcgs mice that differentially express MHC class II glycoproteins. Several different criteria were used to evaluate the presentation of a protein antigen, ovalbumin (OVA), including limiting the concentration of antigen or the numbers of macrophages, and using both native OVA and OVA peptide 323-339. No differences in the capacity of macrophages from Bcgr and Bcgs mice to present antigen to a OVA-specific T cell hybridoma were found. Splenic macrophages from BCG-infected congenic mice also induced an equivalent amount of IL-2 production by the T cell hybridoma. The relationship of these findings to other differences that have been attributed to Bcg are discussed.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-1716521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-1757110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-1937752,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2115416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2115981,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2118680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2499628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2686679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2850122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-2972781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3127465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3141269,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3284817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3496165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3543128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3882240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-3930641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-6166712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-6332146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-7045675,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-8476568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8187331-8490962
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-9104
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8187331-Animals,
pubmed-meshheading:8187331-Antigen Presentation,
pubmed-meshheading:8187331-Antigens, Bacterial,
pubmed-meshheading:8187331-Chloroquine,
pubmed-meshheading:8187331-Histocompatibility Antigens Class II,
pubmed-meshheading:8187331-Immunity, Innate,
pubmed-meshheading:8187331-Interferon-gamma,
pubmed-meshheading:8187331-Macrophages,
pubmed-meshheading:8187331-Mice,
pubmed-meshheading:8187331-Mice, Inbred BALB C,
pubmed-meshheading:8187331-Mycobacterium bovis,
pubmed-meshheading:8187331-Ovalbumin,
pubmed-meshheading:8187331-Peptide Fragments,
pubmed-meshheading:8187331-Spleen
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pubmed:year |
1994
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pubmed:articleTitle |
Antigen presentation by macrophages from bacille Calmette-Guérin (BCG)-resistant and -susceptible mice.
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pubmed:affiliation |
Department of Microbiology, College of Biological Sciences, Ohio State University, Columbus 43210.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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