Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-6-21
pubmed:abstractText
Using intact, urethane-anesthetized albino rats, we examine long-term depression (LTD) of the ipsilateral medial entorhinal cortical (MEC) response in the dentate gyrus (DG) that is induced by conditioning of the ipsilateral lateral entorhinal cortex (LEC). Although the LEC-DG response potentiates, conditioning the LEC induces little or no LTD of the MEC-DG response. However, bicuculline methiodide, and the correlated presence of population spikes, enable the LEC input to induce LTD of the MEC-DG response. This result suggests that inhibition can control the selectivity of translaminar interactions.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
613
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
309-12
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Bicuculline permits the induction of long-term depression by heterosynaptic, translaminar conditioning in the hippocampal dentate gyrus.
pubmed:affiliation
Department of Neurological Surgery, University of Virginia, Charlottesville 22908.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.