| pubmed-article:8183892 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0041178 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0035696 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C1415587 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0150312 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C1519595 | lld:lifeskim |
| pubmed-article:8183892 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:8183892 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:8183892 | pubmed:dateCreated | 1994-6-16 | lld:pubmed |
| pubmed-article:8183892 | pubmed:abstractText | The HLA-G monomorphic, nonclassical class I gene encodes the major histocompatibility complex (MHC) molecule, which is the only MHC antigen expressed on cytotrophoblast cells of placenta. In this work, we have investigated expression of the HLA-G gene in fetal tissues and adult peripheral blood cells by using a sensitive hot-start reverse transcriptase PCR technique. PCR amplification with HLA-G primers specific for exon 3 has enabled us to demonstrate an alternatively spliced form of HLA-G mRNA present in fetal first trimester trophoblasts and lacking exon 4 (HLA-G.3-5). This low abundance transcript (approximately 1:200) in comparison to full-length mRNA may encode the protein that excludes the alpha 3 domain and by conformational changes may present a different ability to bind to peptides. Moreover, expression of the HLA-G transcript was found in adult peripheral lymphocytes and equally in B- and T-cell populations. These results are discussed in the context of the fetal-maternal relationship presented by HLA-G gene products. | lld:pubmed |
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| pubmed-article:8183892 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8183892 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8183892 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8183892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8183892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8183892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8183892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8183892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8183892 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8183892 | pubmed:month | May | lld:pubmed |
| pubmed-article:8183892 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:8183892 | pubmed:author | pubmed-author:GluckmanEE | lld:pubmed |
| pubmed-article:8183892 | pubmed:author | pubmed-author:DaussetJJ | lld:pubmed |
| pubmed-article:8183892 | pubmed:author | pubmed-author:CarosellaEE | lld:pubmed |
| pubmed-article:8183892 | pubmed:author | pubmed-author:MoreauPP | lld:pubmed |
| pubmed-article:8183892 | pubmed:author | pubmed-author:KirszenbaumMM | lld:pubmed |
| pubmed-article:8183892 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8183892 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:8183892 | pubmed:volume | 91 | lld:pubmed |
| pubmed-article:8183892 | pubmed:geneSymbol | HLA-A | lld:pubmed |
| pubmed-article:8183892 | pubmed:geneSymbol | HLA-B | lld:pubmed |
| pubmed-article:8183892 | pubmed:geneSymbol | HLA-G | lld:pubmed |
| pubmed-article:8183892 | pubmed:geneSymbol | HLA-C | lld:pubmed |
| pubmed-article:8183892 | pubmed:geneSymbol | HLA-E | lld:pubmed |
| pubmed-article:8183892 | pubmed:geneSymbol | HLA-F | lld:pubmed |
| pubmed-article:8183892 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8183892 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8183892 | pubmed:pagination | 4209-13 | lld:pubmed |
| pubmed-article:8183892 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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