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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1994-6-14
|
| pubmed:abstractText |
Three new biflavonoids to which we have accorded the trivial names calycopterone (1), isocalycopterone (2), and 4-demethylcalycopterone (3) and the known flavone 4',5-dihydroxy-3,3',6,7-tetramethoxyflavone (4) were isolated as cytotoxic constituents from the flowers of Calycopteris floribunda Lamk. (Combretaceae). Compounds 1-3 showed a wide range of activity against a panel of solid tumor cell lines. Among the biflavonoids, calycopterone (1) is the major constituent.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0022-2623
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
13
|
| pubmed:volume |
37
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
1465-70
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8182705-Animals,
pubmed-meshheading:8182705-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:8182705-Benzopyrans,
pubmed-meshheading:8182705-Drug Screening Assays, Antitumor,
pubmed-meshheading:8182705-Flavonoids,
pubmed-meshheading:8182705-Humans,
pubmed-meshheading:8182705-Mice,
pubmed-meshheading:8182705-Models, Molecular,
pubmed-meshheading:8182705-Molecular Conformation,
pubmed-meshheading:8182705-Tumor Cells, Cultured
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Plant antitumor agents. 31. The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human tumor cell lines.
|
| pubmed:affiliation |
Research Triangle Institute, Research Triangle Park, North Carolina 27709.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|