Linked Life Data

8181533

Source:http://linkedlifedata.com/resource/pubmed/id/8181533

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-6-14
pubmed:abstractText
The number of peripheral T cells in mice increases up to 100-fold in the first few weeks of life. We have followed the fate of Thy-1 congenic T cells transferred into newborn recipients, to evaluate the relative contribution of thymic output versus peripheral expansion in the constitution of peripheral T cell pools during post-natal development. The results show that in normal animals there is essentially no peripheral expansion of T cells, which show slow turnover rates (1 to 2 months) along that time period. The rates of cell accumulation in the periphery require, therefore, an average of 1 x 10(6)-2 x 10(6) mature thymic emigrants/day for the first 3 weeks of life.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0014-2980
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1223-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Differential contribution of thymic outputs and peripheral expansion in the development of peripheral T cell pools.
pubmed:affiliation
Unité d'Immunobiologie, CNRS URA 359, Institut Pasteur, Paris, France.
pubmed:publicationType
Journal Article