Linked Life Data

8177978

Source:http://linkedlifedata.com/resource/pubmed/id/8177978

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-6-9
pubmed:abstractText
The past 5 years has witnessed marked progress toward a higher understanding of the vitamin D endocrine system. Presently, we have a more complete picture of the VDR itself, the DNA sequences to which it binds, and the other coreceptors with which it interacts. This last feature is perhaps the most startling recent development in the vitamin D endocrine system. It clearly suggests a potential role for retinoids and their vitamin A-derived ligands in the mechanism of vitamin D action. These two fat-soluble vitamins not only have quite discrete functionalities, but they may also play requisite roles in the pathway of each other. This is particularly intriguing because the actions of vitamin D were attributed originally to vitamin A. Only later were these two vitamins functionally dissected. Now, approximately 75 years later, the emerging data suggest that selected actions of these two fat-soluble vitamins may indeed be linked.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0270-9295
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
101-18
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
New insight into the structure and functions of the vitamin D receptor.
pubmed:affiliation
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review