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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1994-6-6
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pubmed:abstractText |
Although bone scintigraphy with 99mTc-MDP is a sensitive diagnostic method to detect bone metastasis, it is not specific for malignancy. A radioactive substance which accumulates specifically into metastatic lesions should be of value. 123I-IMP and bone scintigraphy with 99mTc-MDP were consecutively performed in patients with vertebral bone metastases from hepatocellular carcinoma and lumbar spondylosis deformans in a 7-day interval or shorter. The intensity of uptake was compared. Eighteen of the 20 metastatic lesions (90%) were classified as increased uptake areas in 123I-IMP scintigraphy. MDP-scintigraphy disclosed 16 metastatic lesions (80%), 9 as "hot" lesions (56%) and 7 as "cold" lesions (44%). 123I-IMP scintigraphy was negative in all 12 lesions of lumbar spondylosis deformans. Compared to MDP-scintigraphy, 123I-IMP scintigraphy was more sensitive in detecting vertebral bone metastases of hepatocellular carcinoma with smaller rates of false-positive and false-negative findings.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0284-1851
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
159-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8172743-Amphetamines,
pubmed-meshheading:8172743-Carcinoma, Hepatocellular,
pubmed-meshheading:8172743-Female,
pubmed-meshheading:8172743-Humans,
pubmed-meshheading:8172743-Iodine Radioisotopes,
pubmed-meshheading:8172743-Iofetamine,
pubmed-meshheading:8172743-Liver Neoplasms,
pubmed-meshheading:8172743-Male,
pubmed-meshheading:8172743-Middle Aged,
pubmed-meshheading:8172743-Spinal Neoplasms,
pubmed-meshheading:8172743-Technetium Tc 99m Medronate
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pubmed:year |
1994
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pubmed:articleTitle |
Clinical experience of 123I-IMP scintigraphy in detecting vertebral bone metastases of hepatocellular carcinoma. A comparison with bone scintigraphy with 99mTc-MDP.
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pubmed:affiliation |
Department of Radiology, Tottori University Faculty of Medicine, Yonago, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
|