Linked Life Data

8171267

Source:http://linkedlifedata.com/resource/pubmed/id/8171267

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-5-27
pubmed:abstractText
Male Wistar rats were submitted to complete hindlimb ischaemia for 4.5 h. Six animals were injected with antineutrophilic serum (ANS) pre- and post-operatively, and eight animals received normal sheep serum (NSS). The rats were killed 72 h after the insult, and the areas of necrosis in the anterior tibial muscles were measured morphometrically on histological slides. In the NSS group there was a considerable postoperative increase in polymorphonuclear leukocytes (PMNLs) in peripheral blood, while treatment with ANS resulted in total depletion of PMNLs during ischaemia and early reperfusion. There was 31% necrosis in the NSS group and 28% necrosis in the ANS group. This difference was not significant (p = 0.7). It is concluded that depletion of PMNLs had no effect on the infarct size in the anterior tibial muscle after 4.5 h of complete hindlimb ischaemia and 72 h of reperfusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0036-5513
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-22
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Does granulocyte depletion protect against ischaemic muscle necrosis?
pubmed:affiliation
Institute for Surgical Research, Rikshospitalet (The National Hospital), Oslo, Norway.
pubmed:publicationType
Journal Article