Linked Life Data

8168180

Source:http://linkedlifedata.com/resource/pubmed/id/8168180

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-6-1
pubmed:abstractText
The relationship between atypical proliferation and carcinogenesis of colonic mucous membrane glands induced by different doses of 1,2-dimethylhydrazine (DMH) was studied by use of histopathological methods and sequential endoscopic observation. The results showed a significant increase of atypical glands in the flat mucosa with the increase in number of DMH injections, the degree of atypical proliferation becoming more serious with the increase of glandular ducts. The following changes were observed under sequential endoscopy: small elevations were first seen on the flat mucosa, then in sequence-flat elevations, hemisphere elevations, substem elevations and finally, stemmed elevations. At the same time, changes such as rubifaction, erosion, central depression and hemorrhage on the tumor surface were frequently encountered. It is concluded that atypical glandular proliferation in the flat mucosa of the colon is a precancerous lesion of colonic carcinoma.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0529-5807
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
218-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[A histogenetic study on the carcinogenesis of colonic mucous membrane glands induced by 1,2-dimethylhydrazine in rats].
pubmed:affiliation
Department of Laser, 3rd. Teaching Hospital, Norman Bethune University of Medical Sciences, Changchun.
pubmed:publicationType
Journal Article, English Abstract