Linked Life Data

8167121

Source:http://linkedlifedata.com/resource/pubmed/id/8167121

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 1
pubmed:dateCreated
1994-6-2
pubmed:abstractText
To evaluate the efficacy of University of Wisconsin solution for clinical heart transplantation, load-independent parameters were used to assess left ventricular function after transplantation. Donor hearts were arrested with and stored in buffered cold cardioplegic solution for control (n = 5) and University of Wisconsin solution for the experimental group (n = 5). Orthotopic transplantations were performed in a routine manner. Mean donor age (cardioplegic solution, 28 +/- 5.2 years; University of Wisconsin solution, 28 +/- 5.1 years) and ischemic times (cardioplegic solution, 181 +/- 27 minutes; University of Wisconsin solution, 224 +/- 23 minutes) were similar. Two hours after reperfusion of the heart, transesophageal echocardiography was used to image the left ventricle at the mid-papillary muscle level, and a high-fidelity catheter-tipped manometer was placed in the left ventricle to record left ventricular pressure simultaneously. These images were digitized during apneic baseline conditions and during an acute reduction in preload from inferior vena caval occlusion. The left ventricular cross-sectional areas were measured and matched with left ventricular pressure from the catheter-tipped manometer to reveal pressure-area relationships. The baseline parameters fractional area change and stroke force were calculated. End-systolic elastance, the slope of end-systolic pressure-area relationship and preload recruitable stroke force, the slope of stroke force versus end-diastolic area were calculated from the inferior vena cava occlusion measurements.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1053-2498
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
150-5; discussion 155-6
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:8167121-Adenosine, pubmed-meshheading:8167121-Adolescent, pubmed-meshheading:8167121-Adult, pubmed-meshheading:8167121-Allopurinol, pubmed-meshheading:8167121-Cardioplegic Solutions, pubmed-meshheading:8167121-Echocardiography, Transesophageal, pubmed-meshheading:8167121-Female, pubmed-meshheading:8167121-Glutathione, pubmed-meshheading:8167121-Graft Rejection, pubmed-meshheading:8167121-Graft Survival, pubmed-meshheading:8167121-Heart Arrest, Induced, pubmed-meshheading:8167121-Heart Transplantation, pubmed-meshheading:8167121-Humans, pubmed-meshheading:8167121-Insulin, pubmed-meshheading:8167121-Male, pubmed-meshheading:8167121-Middle Aged, pubmed-meshheading:8167121-Organ Preservation, pubmed-meshheading:8167121-Organ Preservation Solutions, pubmed-meshheading:8167121-Raffinose, pubmed-meshheading:8167121-Signal Processing, Computer-Assisted, pubmed-meshheading:8167121-Stroke Volume, pubmed-meshheading:8167121-Survival Rate, pubmed-meshheading:8167121-Time Factors, pubmed-meshheading:8167121-Ventricular Function, Left, pubmed-meshheading:8167121-Ventricular Pressure
pubmed:articleTitle
A clinical trial comparing University of Wisconsin solution and cold cardioplegic solution with load-independent mechanical parameters.
pubmed:affiliation
Department of Surgery, University of Pittsburgh Medical Center, Pa.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial