Linked Life Data

816692

Source:http://linkedlifedata.com/resource/pubmed/id/816692

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1976-7-6
pubmed:abstractText
Within the framework of a study on the immunostimulant properties of Brucella abortus and of its extracts, we have investigated the protective activity on infection of mice by Klebsiella pneumoniae and on Charlotte Friend's leukemia, of inactivated Brucella abortus and brucella lysates by ultrasound. The injection of inactivated B 19 R preparations and their lysates three days before infection by klebsiella has allowed to protect mice against a large number of DL50 (100 and 1000 in certain cases). To determine the role of the surface antigen in this type of immunostimulant, the activity of the B 19 R inactivated preparations has also been examined. It appears that the protection obtained by the injection on day J + 3, in relation to the infection, does not depend on the presence of the complete surface antigen, while the long term effect seems to be more dependent on this. The development of Charlotte Friend's leukemia has been favourably influenced by the previous injection of B 19 S or inactivated B 19 R. Immunotherapy on days J + 1 or J + 3 gave encouraging results with B 19 R, but facilitation with B 19 S. These results confirm the immunostimulant activity of brucella which has already been reported by ourselves and by other authors.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-5149
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61, 399-407
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
[Brucella and modification of the host response to bacterial and viral infection. Effect of the S-R variation].
pubmed:publicationType
Journal Article, English Abstract