Linked Life Data

8166461

Source:http://linkedlifedata.com/resource/pubmed/id/8166461

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1A
pubmed:dateCreated
1994-5-26
pubmed:abstractText
Histologically intact human adenocarcinoma of the lung maintained in nude mice by serial subcutaneous transplantations (4 generations) was harvested and transplanted to the parietal pleura of 11 other nude mice via a novel thoracotomy procedure. Local and regional tumor growth of transplanted tumors occurred in all cases within 31 days, resulting in weight loss, decreased physical activity and death. This rapid-growth "patient-like" model of direct transplantation of a human neoplasm to the parietal pleura may facilitate basic research of pleural malignancies, and stimulate studies of pleural tumor response to cytotoxic treatment, biologic modifiers, and other modalities of treatment. and other modalities of treatment.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-91
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
A "patient-like" nude mouse model of parietal pleural human lung adenocarcinoma.
pubmed:affiliation
Department of Pulmonary and Critical Care Medicine, UCSD Medical Center, San Diego 92093-069.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.