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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1994-5-23
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pubmed:abstractText |
We investigated the possibility that a significant proportion of children with osteosarcoma harbor germline mutations of the p53 tumor suppressor gene and, therefore, this subgroup of pediatric cancer patients should be considered for large-scale predictive testing.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0732-183X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
925-30
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8164043-Base Sequence,
pubmed-meshheading:8164043-Child,
pubmed-meshheading:8164043-Codon,
pubmed-meshheading:8164043-DNA, Neoplasm,
pubmed-meshheading:8164043-DNA Mutational Analysis,
pubmed-meshheading:8164043-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:8164043-Exons,
pubmed-meshheading:8164043-Genes, p53,
pubmed-meshheading:8164043-Heterozygote,
pubmed-meshheading:8164043-Humans,
pubmed-meshheading:8164043-Molecular Sequence Data,
pubmed-meshheading:8164043-Mutation,
pubmed-meshheading:8164043-Osteosarcoma,
pubmed-meshheading:8164043-Polymerase Chain Reaction,
pubmed-meshheading:8164043-Sequence Analysis, DNA
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pubmed:year |
1994
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pubmed:articleTitle |
Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma.
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pubmed:affiliation |
Division of Molecular Genetics, Massachusetts General Hospital, Boston 02129.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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