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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1994-5-26
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pubmed:abstractText |
Calbindin antibodies have been used in neuroanatomical studies to give excellent cytoarchitectural staining and visualization of a Golgi-like cellular morphology. Calbindin-D28K immunoreactivity used in rat pineal gland as a marker detected two classes of pineal cells. One class of small cells representing exclusively glial cells was strongly immunoreactive, and presented a large variety of individual shapes. The majority were a pyramidal shape with one or more processes while others displayed a cytoplasmic lipid droplet. Some small cells occurred around pericapillary spaces. The second class of calbindin-D28K positive cells corresponding to type II pinealocytes were characterized by their large size and less intensive labelling. Type II pinealocytes were round or rectangular; the nucleus was infolded and large with a prominent nucleolus. These large cells were preferentially distributed in the vicinity of vessels and assembled in a cluster of more than ten cells. The lack of S-100 and myeloperoxidase immunoreactivities in large calbindin-D28K cells excluded their possible characterization as glial cells and mononuclear phagocytes, while their size (> 15 microns) excluded microglial cells. A sex difference was detected between large calbindin-D28K positive cells. The mean calculated number of large positive cells for males was 6361 +/- 1504 (n = 8) compared to 2162 +/- 1235 (n = 7) for females. No significative difference was detected between males and females for small calbindin-D28K positive cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Protein, Vitamin...,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxidase,
http://linkedlifedata.com/resource/pubmed/chemical/S100 Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/calbindin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0301-5564
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
449-55
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8163388-Animals,
pubmed-meshheading:8163388-Biological Markers,
pubmed-meshheading:8163388-Calcium-Binding Protein, Vitamin D-Dependent,
pubmed-meshheading:8163388-Female,
pubmed-meshheading:8163388-Immunohistochemistry,
pubmed-meshheading:8163388-Male,
pubmed-meshheading:8163388-Peroxidase,
pubmed-meshheading:8163388-Pineal Gland,
pubmed-meshheading:8163388-Rats,
pubmed-meshheading:8163388-Rats, Wistar,
pubmed-meshheading:8163388-S100 Proteins,
pubmed-meshheading:8163388-Sex Characteristics
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pubmed:year |
1993
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pubmed:articleTitle |
Sexual dimorphism among calbindin-D28K immunoreactive cells in the rat pineal body.
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pubmed:affiliation |
Laboratoire d'Histologie, Faculté de Médecine, Université libre de Bruxelles, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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