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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-5-24
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pubmed:abstractText |
Twelve consecutive patients undergoing elective cardiac surgery were perfused with the Cobe Optima hollow fibre oxygenator. Gas transfer characteristics and blood handling were studied. The device had a maximum oxygen transfer of 315 ml/minute. The average shunt fraction was 4.5%, and was not influenced by blood-flow rate. Mean platelet count declined slightly to 91% of the baseline at the end of the study period. Haemolysis was evaluated by monitoring serum-free haemoglobin, serum haptoglobin and serum haemopexin. The evolution was as follows: free haemoglobin increased from 14 +/- 5 mg/100 ml to 85 +/- 0.8/100 ml (p = 0.01) at the end of bypass; haptoglobin decreased from 1.33 +/- 0.90 g/l to 0.89 +/- 0.15 g/l (p = 0.01); and haemopexin decreased from 0.84 +/- 0.13 g/l to 0.74 +/- 0.15 g/l (p = nonsignificant). In all patients the residual capacity of serum haptoglobin to protect against haemolysis was satisfactory. All patients had an uneventful postoperative course.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0267-6591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-64
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8161869-Aged,
pubmed-meshheading:8161869-Blood Gas Analysis,
pubmed-meshheading:8161869-Evaluation Studies as Topic,
pubmed-meshheading:8161869-Extracorporeal Membrane Oxygenation,
pubmed-meshheading:8161869-Female,
pubmed-meshheading:8161869-Hematologic Tests,
pubmed-meshheading:8161869-Hemolysis,
pubmed-meshheading:8161869-Humans,
pubmed-meshheading:8161869-Male,
pubmed-meshheading:8161869-Middle Aged,
pubmed-meshheading:8161869-Prospective Studies
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pubmed:year |
1994
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pubmed:articleTitle |
Clinical evaluation of a new hollow fibre membrane oxygenator.
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pubmed:affiliation |
Department of Perfusion, University Hospital Gent, Belgium.
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pubmed:publicationType |
Journal Article
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